Improving Adherence in an Intelligent Way


Human beings forget to do things. Sometimes they forget even very important things. If you’re lucky it won’t matter and maybe no one will ever know the difference. However, if you’re one of the more than 1 million Americans that have inflammatory bowel disease (IBD) or countless other diseases that require regular medication to manage, forgetting to take your medication can change the course of your life [1].

The problem

Medication adherence is a major problem in our healthcare system. For example, in IBD it has been shown that only 40% of patients are adequately compliant and non-adherence leads to a 5-fold increase in the risk of suffering exacerbation of the disease [2]. On top of that, it has been shown that the majority of non-adherence occurs because patients forget doses [3].

A proven track record

While it may not be our sexiest or most innovative intervention, medication tracking is unique in that the relatively simple idea of using text messages to improve medication adherence has been studied extensively over the past 12 years and the scientific foundation for its efficacy is clear (one integrative review of 10 years’ worth of articles found 9 out of 13 studies with improvements in adherence rates between 15.3-17.8%) [4].

What Sets Epharmix Apart

When a patient responds that they have missed a dose of their medication, the Epharmix medication tracking system goes beyond simple medication reminding and goes through a differential diagnosis for why that patient missed their dose. This gives providers real time insight into when a patient may be out of meds, when a potential adverse drug reaction is occurring, or when a patient may mistakenly believe they don’t need to take their medication anymore because they are feeling better. Catching these critical events early before they have a chance to impact patients’ lives, while improving the day to day adherence of patients, makes the Epharmix medication tracking system a powerful tool for maintaining a healthier patient population.


  2. Kane S, Huo D, Aikens J, et al.. Medication nonadherence and the outcomes of patients with quiescent ulcerative colitis. Am J Med. 2003;114:39–43.
  3. Kane SV, Cohen RD, Aikens JE, et al. Prevalence of nonadherence with maintenance mesalamine in quiescent ulcerative colitis. Am J Gastroenterol. 2001;96:2929–2933.
  4. Dekoekkoek, Tracy, Barbara Given, Charles W. Given, Kimberly Ridenour, Monica Schueller, and Sandra L. Spoelstra. “MHealth SMS Text Messaging Interventions and to Promote Medication Adherence: An Integrative Review.” J Clin Nurs Journal of Clinical Nursing19-20 (2015): 2722-735. Web.

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